Nuclear analytical techniques applied to nanotoxicology research
Scientists from the Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety at Systematic platform using integrated advanced nuclear techniques for nanotoxicology
Systematic platform using integrated advanced nuclear techniques for nanotoxicology
In the paper, scientists present a comprehensive overview of nuclear analytical techniques applied to the physicochemical characterization of nanomaterials, structural analysis of bio-nano interactions, visualization of nanomaterials in vitro, quantification of bio-distribution, bio-accumulation, and
transformation of nanomaterials in vivo. As important complementary tools, optical imaging technologies are also highlighted. Future directions regarding advanced nuclear analytical approaches for nanotoxicology are also discussed.
Because of their advantages of absolute quantification, high sensitivity, excellent accuracy and precision, low matrix effects and non-destructiveness, nuclear analytical techniques have been playing important roles in the study of nanotoxicology.